Abstract on our antibacterial fiber accepted at MHSRS

Our abstract titled "Antimicrobial Development to Counter Wound Infections in Military Personnel - Electroceutical Suture Fiber for Inflammation Prevention in Complex Wounds: Design, Development, and In-vitro Efficacy" was accepted at the Military Health System Research Symposium (MHSRS) 2022 conferenceur abstract titled "Antimicrobial Development to Counter Wound Infections in Military Personnel - Electroceutical Suture Fiber for Inflammation Prevention in Complex Wounds: Design, Development, and In-vitro Efficacy" was accepted at the Military Health System Research Symposium (MHSRS) 2022 conference from the 12th to the 15th of September. MHSRS is an annual conference that fosters civilian and military state-of-the-art research and development of medical needs for soldiers. Topic areas include: Combat Casualty Care, Military Operational Medicine, Clinical and Rehabilitative Medicine, Medical Simulation and Information Sciences, Military Infectious Diseases, and the Radiation Health Effects.

We will present an antiseptic fiber that can serve as surgical suture wire. The suture cladding is made of biocompatible electrically insulating polymer, encapsulating a pair of chemically dissimilar metallic micro-wires spanning its entire length. Micro-windows, periodically distributed along the suture, penetrate the cladding to expose the wires locally to the exterior. Stitching a cut, in its moist environment, such suture would develop an electric field at its periphery through the galvanic effect, disturning quorum sensing of pathoenic bacteria, and thus mitigate risks of infections in deep wounds, through electroceutical function. This suture will accelerate healing of superficial scars and allow treating deep tissue chronic inflammation in a minimally invasive way.